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Inside Cover: Ceria–Zirconia Nanoparticles as an Enhanced Multi‐Antioxidant for Sepsis Treatment (Angew. Chem. Int. Ed. 38/2017)
Author(s) -
Soh Min,
Kang DongWan,
Jeong HanGil,
Kim Dokyoon,
Kim Do Yeon,
Yang Wookjin,
Song Changyeong,
Baik Seungmin,
Choi InYoung,
Ki SeulKi,
Kwon Hyek Jin,
Kim Taeho,
Kim Chi Kyung,
Lee SeungHoon,
Hyeon Taeghwan
Publication year - 2017
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201706482
Subject(s) - reactive oxygen species , cubic zirconia , nanoparticle , int , sepsis , scavenger , antioxidant , materials science , chemistry , nanotechnology , chemical engineering , medicine , biochemistry , immunology , metallurgy , computer science , ceramic , engineering , operating system
Ceria‐‐zirconia nanoparticles 2 nm in size and with an increased Ce 3+ ratio exhibit greatly enhanced scavenging performance for reactive oxygen species (ROS). In their Communication on page 11399 ff., S.‐H. Lee, T. Hyeon et al. report the superiority of Ce 0.7 Zr 0.3 O 2 nanoparticles in regulating inflammatory cells. They work as a potent ROS scavenger for multiple organ dysfunction in sepsis by reducing the mortality and inflammatory responses.