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Cover Picture: 3‐Aminodeoxypyranoses in Glycosylation: Diversity‐Oriented Synthesis and Assembly in Oligosaccharides (Angew. Chem. Int. Ed. 19/2017)
Author(s) -
Zeng Jing,
Sun Guangfei,
Yao Wang,
Zhu Yangbin,
Wang Ruobin,
Cai Lei,
Liu Ke,
Zhang Qian,
Liu XueWei,
Wan Qian
Publication year - 2017
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201702798
Subject(s) - glycosylation , aminosugar , chemistry , total synthesis , drug discovery , convergent synthesis , stereochemistry , combinatorial chemistry , biochemistry , glucosamine
Tetrasaccharides containing different 3‐aminosugar components have been assembled by diversity‐oriented synthesis and Yu glycosylation reactions. In their Communication on page 5227 ff., J. Zeng, Q. Wan, and co‐workers describe a new type of key intermediate that provides access to naturally occurring 3‐aminosugars and analogues thereof. These aminosugars were used in glycosylation reactions and should find applications in drug discovery.