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Cyclic (Alkyl)(amino)carbenes (CAACs): Recent Developments
Author(s) -
Melaimi Mohand,
Jazzar Rodolphe,
Soleilhavoup Michèle,
Bertrand Guy
Publication year - 2017
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201702148
Subject(s) - electrophile , nucleophile , alkyl , chemistry , diamagnetism , catalysis , molecule , paramagnetism , combinatorial chemistry , stereochemistry , medicinal chemistry , organic chemistry , physics , quantum mechanics , magnetic field
Discovered in 2005, cyclic (alkyl)(amino)carbenes (CAACs) are among the most nucleophilic (σ donating) and also electrophilic (π‐accepting) stable carbenes known to date. These properties allow them to activate a variety of small molecules and enthalpically strong bonds, to stabilize highly reactive main‐group and transition‐metal diamagnetic and paramagnetic species, and to bind strongly to metal centers, which gives rise to very robust catalysts. The most important results published up to the end of 2013 are briefly summarized, while the majority of this Review focuses on findings reported within the last three years.