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Back Cover: Remote Regulation of Membrane Channel Activity by Site‐Specific Localization of Lanthanide‐Doped Upconversion Nanocrystals (Angew. Chem. Int. Ed. 11/2017)
Author(s) -
Ai Xiangzhao,
Lyu Linna,
Zhang Yang,
Tang Yanxia,
Mu Jing,
Liu Fang,
Zhou Yixi,
Zuo Zhenghong,
Liu Gang,
Xing Bengang
Publication year - 2017
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201701355
Subject(s) - photon upconversion , lanthanide , membrane , int , cover (algebra) , nanocrystal , chemistry , irradiation , nanotechnology , doping , ion , biophysics , materials science , biochemistry , optoelectronics , biology , computer science , physics , engineering , mechanical engineering , organic chemistry , nuclear physics , operating system
Spatiotemporal regulation of membrane channel activity in living systems has been achieved by irradiation with near‐IR light ( λ =808 nm), as reported by B. Xing, G. Liu, and co‐workers in their Communication on page 3031 ff. Metabolic glycan biosynthesis is used to attach lanthanide‐doped upconversion nanocrystals (UCNs) to the cell surface through copper‐free click cyclization. Cation influx can be controlled by irradiation and membrane‐associated activities manipulated in living cells and zebrafish.