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Frontispiece: Uncovering Key Structural Features of an Enantioselective Peptide‐Catalyzed Acylation Utilizing Advanced NMR Techniques
Author(s) -
Procházková Eliška,
Kolmer Andreas,
Ilgen Julian,
Schwab Mira,
Kaltschnee Lukas,
Fredersdorf Maic,
Schmidts Volker,
Wende Raffael C.,
Schreiner Peter R.,
Thiele Christina M.
Publication year - 2016
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201685161
Subject(s) - enantioselective synthesis , acylation , substrate (aquarium) , catalysis , chemistry , nuclear magnetic resonance spectroscopy , stereochemistry , combinatorial chemistry , organic chemistry , biology , ecology
NMR Spectroscopy In their Communication on page 15754 ff., P. R. Schreiner, C. M. Thiele et al. apply newly developed NMR experiments to confirm the mechanism of a highly enantioselective acylation reaction. Dispersion interactions between catalyst and substrate are key to the reaction.