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Back Cover: From Palladium to Brønsted Acid Catalysis: Highly Enantioselective Regiodivergent Addition of Alkoxyallenes to Pyrazolones (Angew. Chem. Int. Ed. 4/2017)
Author(s) -
Zhou Hui,
Wei Zhao,
Zhang Jinlong,
Yang Huameng,
Xia Chungu,
Jiang Gaoxi
Publication year - 2017
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201612284
Subject(s) - pyrazolones , catalysis , enantioselective synthesis , palladium , brønsted–lowry acid–base theory , tsuji–trost reaction , chemistry , allylic rearrangement , organic chemistry , combinatorial chemistry
Two catalytic processes namely, palladium catalysis and Brønsted acid catalysis, lead to different alkylation products in the addition of alkoxyallenes to pyrazolones. In their Communication on page 1077, G. Jiang et al. demonstrate how Pd catalysis provides branched allylic pyrazol‐5‐ones under mild conditions, whereas a chiral Brønsted acid catalyst gives the linear addition products.