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Distal‐Bond‐Selective C−C Activation of Ring‐Fused Cyclopentanones: An Efficient Access to Spiroindanones
Author(s) -
Xia Ying,
Wang Jianbo,
Dong Guangbin
Publication year - 2017
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201611642
Subject(s) - chemistry , ring (chemistry) , cleavage (geology) , stereochemistry , bond cleavage , selectivity , rhodium , catalysis , organic chemistry , materials science , fracture (geology) , composite material
A site‐selective rhodium‐catalyzed C−C activation of ring‐fused cyclopentanones was achieved to afford efficient access to a range of spiroindanones. The use of bulky 2‐amino‐6‐picoline as a cocatalyst is key to the excellent selectivity of this C−C bond cleavage in cyclopentanones.