Cover Picture: Asymmetric Induction by a Nitrogen  14 N/ 15 N Isotopomer in Conjunction with Asymmetric Autocatalysis (Angew. Chem. Int. Ed. 49/2016) | Zendy

Matsumoto Arimasa | Zendy; Ozaki Hanae | Zendy; Harada Shunya | Zendy; Tada Kyohei | Zendy; Ayugase Tomohiro | Zendy; Ozawa Hitomi | Zendy; Kawasaki Tsuneomi | Zendy; Soai Kenso | Zendy

Premium

Cover Picture: Asymmetric Induction by a Nitrogen 14 N/ 15 N Isotopomer in Conjunction with Asymmetric Autocatalysis (Angew. Chem. Int. Ed. 49/2016)

Author(s) -

Matsumoto Arimasa,

Ozaki Hanae,

Harada Shunya,

Tada Kyohei,

Ayugase Tomohiro,

Ozawa Hitomi,

Kawasaki Tsuneomi,

Soai Kenso

Publication year - 2016

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Reports

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201610382

Subject(s) - autocatalysis , chirality (physics) , enantioselective synthesis , chemistry , kinetic isotope effect , asymmetric induction , isotopomers , diamine , nitrogen , stereochemistry , crystallography , organic chemistry , catalysis , deuterium , physics , molecule , chiral symmetry breaking , atomic physics , quantum mechanics , nambu–jona lasinio model , quark

Chirality arising from isotope substitution is usually not considered a source of chirality in a chemical reaction. In their Communication on page 15246 ff., A. Matsumoto, K. Soai, and co‐workers employ a 14 N/ 15 N isotopically chiral diamine, N 2 ,N 2 ,N 3 ,N 3 ‐tetramethyl‐2,3‐butandiamine, as a chiral initiator for an asymmetric autocatalysis reaction. This is the first example of enantioselective induction actuated by the “hidden” chiral effect of nitrogen isotope ( 14 N/ 15 N) substitution.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research