Cover Picture: Asymmetric Induction by a Nitrogen 14 N/ 15 N Isotopomer in Conjunction with Asymmetric Autocatalysis (Angew. Chem. Int. Ed. 49/2016)

Chirality arising from isotope substitution is usually not considered a source of chirality in a chemical reaction. In their Communication on page 15246 ff., A. Matsumoto, K. Soai, and co‐workers employ a 14 N/ 15 N isotopically chiral diamine, N 2 ,N 2 ,N 3 ,N 3 ‐tetramethyl‐2,3‐butandiamine, as a chiral initiator for an asymmetric autocatalysis reaction. This is the first example of enantioselective induction actuated by the “hidden” chiral effect of nitrogen isotope ( 14 N/ 15 N) substitution.