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Palladium(0)‐Catalyzed Intermolecular Arylative Dearomatization of β‐Naphthols
Author(s) -
Xu RenQi,
Yang Ping,
Tu HangFei,
Wang ShouGuo,
You ShuLi
Publication year - 2016
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201608724
Subject(s) - chemoselectivity , intermolecular force , catalysis , palladium , halide , aryl , chemistry , combinatorial chemistry , organic chemistry , alkyl , molecule
The first Pd 0 ‐catalyzed intermolecular arylative dearomatization of β‐naphthols with aryl halides is described. It was found that Q‐Phos could facilitate the palladium‐catalyzed cross‐coupling‐type dearomatization of β‐naphthols, while avoiding O ‐arylation, to construct 2‐naphthalenones in excellent yields and with high chemoselectivity.
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