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Iridium‐Catalyzed Carbonylative Synthesis of Chromenones from Simple Phenols and Internal Alkynes at Atmospheric Pressure
Author(s) -
Zhu Fengxiang,
Li Yahui,
Wang Zechao,
Wu XiaoFeng
Publication year - 2016
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201608715
Subject(s) - iridium , regioselectivity , phenols , annulation , catalysis , atmospheric pressure , chemistry , carbonylation , organic chemistry , combinatorial chemistry , carbon monoxide , physics , meteorology
A novel procedure on the carbonylative synthesis of chromenones has been developed. With simple phenols and internal alkynes as the substrates, various chromenones were isolated in moderate to good yields with excellent regioselectivity and functional‐group tolerance by using iridium as the catalyst and copper as the promotor at atmospheric pressure. Notably, this is the first example on carbonylative annulation of simple phenols and alkynes.