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Liquid Marbles Based on Magnetic Upconversion Nanoparticles as Magnetically and Optically Responsive Miniature Reactors for Photocatalysis and Photodynamic Therapy
Author(s) -
Wang Dan,
Zhu Lin,
Chen JianFeng,
Dai Liming
Publication year - 2016
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201604781
Subject(s) - photodynamic therapy , materials science , nanotechnology , photon upconversion , drug delivery , nanoparticle , opacity , photocatalysis , magnetic nanoparticles , iron oxide nanoparticles , lanthanide , cancer therapy , optoelectronics , doping , optics , chemistry , cancer , catalysis , organic chemistry , medicine , ion , physics
Magnetic liquid marbles have recently attracted extensive attention for various potential applications. However, conventional liquid marbles based on iron oxide nanoparticles are opaque and inadequate for photo‐related applications. Herein, we report the first development of liquid marbles coated with magnetic lanthanide‐doped upconversion nanoparticles (UCNPs) that can convert near‐infrared light into visible light. Apart from their excellent magnetic and mechanical properties, which are attractive for repeatable tip opening and magnetically directed movements, the resultant UCNP‐based liquid marbles can act as ideal miniature reactors for photodynamic therapy of cancer cells. This work opens new ways for the development of liquid marbles, and shows great promise for liquid marbles based on UCNPs to be used in a large variety of potential applications, such as photodynamic therapy for accelerated drug screening, magnetically guided controlled drug delivery and release, and multifunctional actuation.