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Inside Back Cover: Enantioselective Trifluoromethylthiolating Lactonization Catalyzed by an Indane‐Based Chiral Sulfide (Angew. Chem. Int. Ed. 19/2016)
Author(s) -
Liu Xiang,
An Rui,
Zhang Xuelin,
Luo Jie,
Zhao Xiaodan
Publication year - 2016
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201603087
Subject(s) - enantioselective synthesis , sulfide , bifunctional , indane , catalysis , electrophile , reagent , chemistry , amide , stereochemistry , combinatorial chemistry , organic chemistry
A bifunctional chiral sulfide catalyst and a new shelf‐stable electrophilic SCF 3 reagent are used for the enantioselective trifluoromethylthiolating lactonization that is reported by X. Zhao et al. in their Communication on page 5846 ff. The reaction occurs only when the amide and sulfide moieties of the catalyst cooperate like crab claws that work together to catch fish.