Premium
Cover Picture: Nickel‐Catalyzed Dimerization and Alkylarylation of 1,3‐Dienes with Alkyl Fluorides and Aryl Grignard Reagents (Angew. Chem. Int. Ed. 18/2016)
Author(s) -
Iwasaki Takanori,
Min Xin,
Fukuoka Asuka,
Kuniyasu Hitoshi,
Kambe Nobuaki
Publication year - 2016
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201602431
Subject(s) - alkyl , aryl , nickel , chemistry , reactivity (psychology) , reagent , catalysis , molecule , medicinal chemistry , polymer chemistry , organic chemistry , medicine , alternative medicine , pathology
Strong C−F bonds were cut by an anionic nickel complex to incorporate the alkyl chains of the alkyl fluorides into the desired coupling products. In their Communication on page 5550 ff., N. Kambe, T. Iwasaki, and co‐workers describe the nickel‐catalyzed regio‐ and stereoselective multicomponent coupling of alkyl fluorides, aryl Grignard reagents, and two molecules of 1,3‐butadiene, showcasing the unique reactivity of anionic bis(allyl)nickel complexes towards C−F bonds.