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Thermal Responsive Ion Selectivity of Uranyl Peroxide Nanocages: An Inorganic Mimic of K + Ion Channels
Author(s) -
Gao Yunyi,
Szymanowski Jennifer E. S.,
Sun Xinyu,
Burns Peter C.,
Liu Tianbo
Publication year - 2016
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201601852
Subject(s) - chemistry , ion , nanocages , uranyl , selectivity , aqueous solution , inorganic chemistry , isothermal titration calorimetry , qualitative inorganic analysis , analytical chemistry (journal) , organic chemistry , catalysis , biochemistry , chromatography
An actinyl peroxide cage cluster, Li 48+ m K 12 (OH) m [UO 2 (O 2 )(OH)] 60 (H 2 O) n ( m ≈20 and n ≈310; U 60 ), discriminates precisely between Na + and K + ions when heated to certain temperatures, a most essential feature for K + selective filters. The U 60 clusters demonstrate several other features in common with K + ion channels, including passive transport of K + ions, a high flux rate, and the dehydration of U 60 and K + ions. These qualities make U 60 (a pure inorganic cluster) a promising ion channel mimic in an aqueous environment. Laser light scattering (LLS) and isothermal titration calorimetry (ITC) studies revealed that the tailorable ion selectivity of U 60 clusters is a result of the thermal responsiveness of the U 60 hydration shells.