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Cover Picture: Target‐Induced and Equipment‐Free DNA Amplification with a Simple Paper Device (Angew. Chem. Int. Ed. 8/2016)
Author(s) -
Liu Meng,
Hui Christy Y.,
Zhang Qiang,
Gu Jimmy,
Kannan Balamurali,
JahanshahiAnbuhi Sana,
Filipe Carlos D. M.,
Brennan John D.,
Li Yingfu
Publication year - 2016
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201600678
Subject(s) - dna , primer (cosmetics) , simple (philosophy) , applications of pcr , polymerase chain reaction , computational biology , microbiology and biotechnology , computer science , nanotechnology , chemistry , biology , genetics , multiplex polymerase chain reaction , materials science , gene , philosophy , organic chemistry , epistemology
A simple paper‐based device for DNA amplification is described by J. D. Brennan, Y. Li, and co‐workers in their Communication on page 2709 ff. The paper device is printed with all enabling reagents, such as DNA polymerase, circular DNA template, and small building blocks, for building long‐chain DNA molecules for visual detection. DNA amplification is automatically activated upon addition of a test sample that contains the DNA or RNA sequence of interest.