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Inside Cover: Catalytic Molecular Imaging of MicroRNA in Living Cells by DNA‐Programmed Nanoparticle Disassembly (Angew. Chem. Int. Ed. 9/2016)
Author(s) -
He Xuewen,
Zeng Tao,
Li Zhi,
Wang Ganglin,
Ma Nan
Publication year - 2016
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201600456
Subject(s) - microrna , nanoparticle , photoluminescence , dna , nanotechnology , catalysis , cover (algebra) , chemistry , colloidal gold , microbiology and biotechnology , materials science , biophysics , biology , biochemistry , gene , optoelectronics , mechanical engineering , engineering
The sensitive imaging of microRNA in living cells remains challenging because of their low abundance. In their Communication on page 3073 ff., N. Ma and co‐workers demonstrate that microRNA can serve as a catalyst to trigger the disassembly of quantum dots (QDs) and gold nanoparticles with multiple turnovers, which yields significantly amplified QD photoluminescence for microRNA imaging in living cells.