Premium
Chromatographic NMR Spectroscopy with Hollow Silica Spheres
Author(s) -
GonzálezGarcía Tania,
Margola Tommaso,
Silvagni Adriano,
Mancin Fabrizio,
Rastrelli Federico
Publication year - 2016
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201510203
Subject(s) - spheres , materials science , nuclear magnetic resonance spectroscopy , context (archaeology) , spectroscopy , analytical chemistry (journal) , silica gel , chromatography , stationary phase , diffusion , chemistry , organic chemistry , physics , thermodynamics , paleontology , quantum mechanics , astronomy , biology
The use of micrometric hollow silica spheres is described as a strategy to reduce magnetic field inhomogeneities in the context of NMR chromatography. When employed as a stationary phase, hollow silica microspheres allow the use of common solution‐state NMR instruments to measure the diffusion coefficient perturbation induced by the interaction of the analytes with the silica surface.