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Inside Cover: A Case Study of the Likes and Dislikes of DNA and RNA in Self‐Assembly (Angew. Chem. Int. Ed. 50/2015)
Author(s) -
Zuo Hua,
Wu Siyu,
Li Mo,
Li Yulin,
Jiang Wen,
Mao Chengde
Publication year - 2015
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201509584
Subject(s) - rna , nucleic acid , dna , self assembly , cover (algebra) , nanotechnology , dna nanotechnology , chemistry , cover story , microbiology and biotechnology , biology , biochemistry , materials science , engineering , gene , mechanical engineering
Can the methods developed for programmed DNA self‐assembly be applied to the assembly of RNA nanostructures? Yes, albeit with some modifications. In their Communication on page 15118 ff., C. Mao, H. Zuo et al. show that the self‐assembly behavior of an RNA nanomotif is somewhat similar to that of its DNA counterpart, but still significantly different. A thorough investigation of the compositional (RNA vs. DNA) effect is thus needed for further developing nucleic acid nanotechnology.