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Ortho ‐Trialkylstannyl Arylphosphanes by C–P and C–Sn Bond Formation in Arynes
Author(s) -
Li Yuanming,
Chakrabarty Shyamal,
MückLichtenfeld Christian,
Studer Armido
Publication year - 2016
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201509329
Subject(s) - aryne , chemistry , medicinal chemistry
A novel and efficient approach to ortho ‐trialkylstannyl arylphosphanes by the reaction of arynes generated in situ with stannylated phosphanes (R 3 SnPR 2 ) is described. Concurrent CP and CSn bond formation occurs with high yields, and stannylated products are easily transformed into valuable ortho ‐substituted arylphosphanes. The reaction features high efficiency, good regioselectivity, and excellent practicality.