Premium
A Rhodium Nanoparticle–Lewis Acidic Ionic Liquid Catalyst for the Chemoselective Reduction of Heteroarenes
Author(s) -
Karakulina Alena,
Gopakumar Aswin,
Akçok İsmail,
Roulier Bastien L.,
LaGrange Thomas,
Katsyuba Sergey A.,
Das Shoubhik,
Dyson Paul J.
Publication year - 2016
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201507945
Subject(s) - rhodium , catalysis , ionic liquid , chemistry , nanoparticle , furan , combinatorial chemistry , lewis acids and bases , molecule , ring (chemistry) , organic chemistry , ionic bonding , nanotechnology , materials science , ion
We describe a catalytic system composed of rhodium nanoparticles immobilized in a Lewis acidic ionic liquid. The combined system catalyzes the hydrogenation of quinolines, pyridines, benzofurans, and furan to access the corresponding heterocycles, important molecules present in fine chemicals, agrochemicals, and pharmaceuticals. The catalyst is highly selective, acting only on the heteroaromatic ring, and not interfering with other reducible functional groups.