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Intermolecular [2+2+1] Carbonylative Cycloaddition of Aldehydes with Alkynes, and Subsequent Oxidation to γ‐Hydroxybutenolides by a Supported Ruthenium Catalyst
Author(s) -
Miura Hiroki,
Takeuchi Kazuki,
Shishido Tetsuya
Publication year - 2016
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201507814
Subject(s) - ruthenium , catalysis , cycloaddition , intermolecular force , chemistry , photochemistry , organic chemistry , polymer chemistry , molecule
Intermolecular [2+2+1] carbonylative cycloaddition of aldehydes with alkynes and subsequent oxidation to γ‐hydroxybutenolides is achieved using a supported ruthenium catalyst. A ceria‐supported ruthenium catalyst promotes the reaction efficiently, even with an ambient pressure of CO or without external CO, thus giving the corresponding γ‐hydroxybutenolide derivatives in good to high yields. Moreover this catalyst can be reused with no loss of activity.