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Cover Picture: Photoexcited Porphyrins as a Strong Suppressor of β‐Amyloid Aggregation and Synaptic Toxicity (Angew. Chem. Int. Ed. 39/2015)
Author(s) -
Lee Byung Il,
Lee Seongsoo,
Suh Yoon Seok,
Lee Joon Seok,
Kim Aekyeong,
Kwon OYu,
Yu Kweon,
Park Chan Beum
Publication year - 2015
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201507432
Subject(s) - porphyrin , chemistry , amyloid (mycology) , biophysics , small molecule , photodynamic therapy , photochemistry , biochemistry , biology , organic chemistry , inorganic chemistry
Photoexcited porphyrin molecules inhibit β‐amyloid aggregation and rescue postsynaptlc toxicity and behavior defects in the Drosophila Alzheimer’s disease model under blue light. In their Communication on page 11472 ff., C. B. Park, K. Yu et al. present a chemical strategy for photodynamic suppression of β‐amyloid aggregation using photosensitizing molecules.