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Visible‐Light‐Catalyzed Direct Benzylic C(sp 3 )–H Amination Reaction by Cross‐Dehydrogenative Coupling
Author(s) -
Pandey Ganesh,
Laha Ramkrishna
Publication year - 2015
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201506990
Subject(s) - amination , catalysis , visible spectrum , chemistry , photochemistry , photoredox catalysis , amide , coupling reaction , combinatorial chemistry , photocatalysis , organic chemistry , materials science , optoelectronics
A conceptually new and synthetically valuable cross‐dehydrogenative benzylic C(sp 3 )–H amination reaction is reported by visible‐light photoredox catalysis. This protocol employs DCA (9,10‐dicyanoanthracene) as a visible‐light‐absorbing photoredox catalyst and an amide as the nitrogen source without the need of either a transition metal or an external oxidant.