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Thyroid hormones—From Crystal Packing to Activity to Reactivity
Author(s) -
Schweizer Ulrich,
Steegborn Clemens
Publication year - 2015
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201506919
Subject(s) - reactivity (psychology) , hormone , thyroid hormones , thyroid , medicine , endocrinology , chemistry , pathology , alternative medicine
Form and substance : Through observation and careful follow‐up on polymorphic forms of thyroxine (Forms I und II; black C, gray H, violet I, blue N, red O), Mondal and Mugesh have provided a stunningly simple answer to the apparent non‐equivalence of thyroid hormone tablets. Their results further suggest control of deiodinase regioselectivity through the adjustment of torsional angles distant from the reactive bond.
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