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Opportunity Knocks: Organic Chemistry for Fragment‐Based Drug Discovery (FBDD)
Author(s) -
Murray Christopher W.,
Rees David C.
Publication year - 2016
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201506783
Subject(s) - chemistry , drug discovery , fragment (logic) , biochemistry , computer science , programming language
What’s a good fragment? Fragment‐based drug discovery is well‐established within many pharmaceutical, biotech, and academic institutions for generating new drugs. In this Essay, the opportunities and challenges for organic chemists to design and synthesize new fragments are described.