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Catalytic Silylations of Alcohols: Turning Simple Protecting‐Group Strategies into Powerful Enantioselective Synthetic Methods
Author(s) -
Xu LiWen,
Chen Yun,
Lu Yixin
Publication year - 2015
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201504127
Subject(s) - enantioselective synthesis , silylation , silyl ether , stereoselectivity , functional group , chemistry , catalysis , group (periodic table) , organic chemistry , combinatorial chemistry , polymer
In recent years, remarkable progress has been made in the enantioselective silylation of alcohols. Owing to the successful site‐ and stereoselective functionalization of hydroxy groups, silyl ether formations have evolved from being a simple reaction for functional‐group protection into a powerful enantioselective process. In this Minireview, we highlight important recent findings in this emerging field.