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A Universal Approach to Ultrasmall Magneto‐Fluorescent Nanohybrids
Author(s) -
Feld Artur,
Merkl JanPhilip,
Kloust Hauke,
Flessau Sandra,
Schmidtke Christian,
Wolter Christopher,
Ostermann Johannes,
Kampferbeck Michael,
Eggers Robin,
Mews Alf,
Schotten Theo,
Weller Horst
Publication year - 2015
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201503017
Subject(s) - polystyrene , materials science , fluorescence , surface modification , magnetism , quantum dot , nanotechnology , nanocrystal , nanomaterials , emulsion polymerization , nanoparticle , polymerization , particle (ecology) , magnetic nanoparticles , nanoscopic scale , chemical engineering , iron oxide , polymer , optics , physics , composite material , oceanography , quantum mechanics , geology , metallurgy , engineering
Seeded emulsion polymerization is a powerful universal method to produce ultrasmall multifunctional magnetic nanohybrids. In a two‐step procedure, iron oxide nanocrystals were initially encapsulated in a polystyrene (PS) shell and subsequently used as beads for a controlled assembly of elongated quantum dots/quantum rods (QDQRs). The synthesis of a continuous PS shell allows the whole construct to be fixed and the composition of the nanohybrid to be tuned. The fluorescence of the QDQRs and magnetism of iron oxide were perfectly preserved, as confirmed by single‐particle investigation, fluorescence decay measurements, and relaxometry. Bio‐functionalization of the hybrids was straightforward, involving copolymerization of appropriate affinity ligands as shown by immunoblot analysis. Additionally, the universality of this method was shown by the embedment of a broad scale of NPs.