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Nickel‐Catalyzed Cross‐Coupling Reactions of o ‐Carboranyl with Aryl Iodides: Facile Synthesis of 1‐Aryl‐ o ‐Carboranes and 1,2‐Diaryl‐ o ‐Carboranes
Author(s) -
Tang Cen,
Xie Zuowei
Publication year - 2015
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201502502
Subject(s) - aryl , chemistry , nickel , catalysis , carborane , coupling reaction , transition metal , metal , medicinal chemistry , combinatorial chemistry , organic chemistry , alkyl
A nickel‐catalyzed arylation at the carbon center of o ‐carborane cages has been developed, thus leading to the preparation of a series of 1‐aryl‐ o ‐carboranes and 1,2‐diaryl‐ o ‐carboranes in high yields upon isolation. This method represents the first example of transition metal catalyzed C,C′‐diarylation by cross‐coupling reactions of o ‐carboranyl with aryl iodides.