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Inside Cover: Efficient Access to Titanaaziridines by CH Activation of N ‐Methylanilines at Ambient Temperature (Angew. Chem. Int. Ed. 14/2015)
Author(s) -
Manßen Manfred,
Lauterbach Nicolai,
Dörfler Jaika,
Schmidtmann Marc,
Saak Wolfgang,
Doye Sven,
Beckhaus Rüdiger
Publication year - 2015
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201501994
Subject(s) - int , cover (algebra) , titanium , chemistry , catalysis , reaction mechanism , transformation (genetics) , combinatorial chemistry , photochemistry , stereochemistry , organic chemistry , computer science , engineering , biochemistry , mechanical engineering , gene , operating system
Killing two birds with one stoneIn the presence of a bis(η 5 ,η 1 ‐pentafulvene) titanium complex, N ‐methylanilines undergo two bond activation reactions to directly give titanaaziridines. Based on this transformation, S. Doye, R. Beckhaus, et al. report in their Communication on page 4383 ff. the isolation and investigation of all key intermediates of the titanium‐catalyzed hydroaminoalkylation of alkenes. The results represent the first experimental proof of the suggested reaction mechanism of this industrially promising reaction.