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Inside Back Cover: Bioinspired Therapeutic Dendrimers as Efficient Peptide Drugs Based on Supramolecular Interactions for Tumor Inhibition (Angew. Chem. Int. Ed. 14/2015)
Author(s) -
Zhang Xiao,
Zhang Zhijun,
Xu Xianghui,
Li Yunkun,
Li Yachao,
Jian Yeting,
Gu Zhongwei
Publication year - 2015
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201501882
Subject(s) - dendrimer , supramolecular chemistry , peptide , chemistry , in vitro , combinatorial chemistry , nucleic acid , in vivo , biophysics , biochemistry , biology , organic chemistry , molecule , microbiology and biotechnology
Bioinspired therapeutic dendrimers are the first dendritic peptide drugs that can be used for efficient tumor therapy. In their Communication on page 4289 ff., X. Xu, Z. Gu, et al. describe the significant supramolecular interactions between the therapeutic dendrimers and nucleic acids via the tryptophan residues. Furthermore, it is shown that the therapeutic dendrimers are efficient antitumor agents both in vitro and in vivo.