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Palladium‐Catalyzed Asymmetric Reductive Heck Reaction of Aryl Halides
Author(s) -
Yue Guizhou,
Lei Kaining,
Hirao Hajime,
Zhou Jianrong Steve
Publication year - 2015
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201501712
Subject(s) - aryl halide , halide , chemistry , stereoselectivity , aryl , catalysis , palladium , heck reaction , dissociation (chemistry) , cationic polymerization , solvent , organic chemistry , medicinal chemistry , alkyl
Asymmetric reductive Heck reaction of aryl halides is realized in high stereoselectivity. Hydrogen‐bond donors, trialkylammonium salts in a glycol solvent, were used to promote halide dissociation from neutral arylpalladium complexes to access cationic, stereoselective pathways.