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Back Cover: Light‐Induced Protein Dimerization by One‐ and Two‐Photon Activation of Gibberellic Acid Derivatives in Living Cells (Angew. Chem. Int. Ed. 9/2015)
Author(s) -
Schelkle Korwin M.,
Griesbaum Tristan,
Ollech Dirk,
Becht Steffy,
Buckup Tiago,
Hamburger Manuel,
Wombacher Richard
Publication year - 2015
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201500780
Subject(s) - gibberellic acid , chemistry , intracellular , biophysics , botany , biology , biochemistry , germination
Precise spatiotemporal control of intracellular protein dimerization by using light as an external stimulus is possible with the phytohormone gibberellic acid. As R. Wombacher et al. show in their Communication on page 2825 ff., irradiation of gibberellic acid (closed lock) with light or photons sets free the biological activity (open lock) through a one‐ or two‐photon absorption process. The induced conformation change and dimerization is symbolized by the embracing couple (a wood cut by the artist Edvard Munch, 1863–1944).