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A New Class of Enzymes Discovered: A Non‐Heme Oxidase Produces Medium‐Chain 1‐Alkenes
Author(s) -
Kourist Robert
Publication year - 2015
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201500466
Subject(s) - lauric acid , biochemistry , heme , chemistry , oxidase test , enzyme , pseudomonas fluorescens , combinatorial chemistry , stereochemistry , biology , bacteria , fatty acid , genetics
The recently discovered non‐heme oxidase UndA catalyzes the conversion of lauric acid into 1‐undecene. For the discovery, an impressive number of 6000 bacterial clones bearing a genome library of Pseudomonas fluorescens had to be screened by gas chromatography. The discovery of UndA is a breakthrough, as it paves the way towards the biotechnological production of medium‐chain 1‐alkenes from renewable materials.