A New Class of Enzymes Discovered: A Non‐Heme Oxidase Produces Medium‐Chain 1‐Alkenes | Zendy

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A New Class of Enzymes Discovered: A Non‐Heme Oxidase Produces Medium‐Chain 1‐Alkenes

Author(s) -

Kourist Robert

Publication year - 2015

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201500466

Subject(s) - lauric acid , biochemistry , heme , chemistry , oxidase test , enzyme , pseudomonas fluorescens , combinatorial chemistry , stereochemistry , biology , bacteria , fatty acid , genetics

The recently discovered non‐heme oxidase UndA catalyzes the conversion of lauric acid into 1‐undecene. For the discovery, an impressive number of 6000 bacterial clones bearing a genome library of Pseudomonas fluorescens had to be screened by gas chromatography. The discovery of UndA is a breakthrough, as it paves the way towards the biotechnological production of medium‐chain 1‐alkenes from renewable materials.

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