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Frontispiece: A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage
Author(s) -
Chandra Koushik,
Roy Tapta Kanchan,
Shalev Deborah E.,
Loyter Abraham,
Gilon Chaim,
Gerber R. Benny,
Friedler Assaf
Publication year - 2014
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201483671
Subject(s) - trifluoroacetic acid , tandem , cleavage (geology) , in situ , chemistry , peptide , combinatorial chemistry , stereochemistry , organic chemistry , biochemistry , materials science , fracture (geology) , composite material
Tandem Peptide Cyclization A. Friedler et al. describe in their Communication on page 9450 ff. a tandem strategy involving in situ deprotection, cyclization, and trifluoroacetic acid cleavage for the solid‐phase cyclization of peptides under highly acidic conditions.