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Falling‐Solid Flash Vacuum Pyrolysis: An Efficient Preparation of Arylacetylenes
Author(s) -
Wentrup Curt,
Becker Jürgen,
Winter HansWilhelm
Publication year - 2015
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201412431
Subject(s) - flash vacuum pyrolysis , pyrolysis , flash (photography) , aldehyde , falling (accident) , chemistry , solid acid , organic chemistry , combinatorial chemistry , chemical engineering , catalysis , physics , optics , engineering , medicine , environmental health
Automated falling‐solid flash vacuum pyrolysis allows the rapid and efficient synthesis of a variety of arylacetylenes from 4‐arylmethylidene‐5(4 H )‐isoxazolone derivatives, which were prepared from aldehyde precursors. The acetylenes are readily obtained in multigram quantities.