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Rhodium(III)‐Catalyzed Cyclative Capture Approach to Diverse 1‐Aminoindoline Derivatives at Room Temperature
Author(s) -
Zhao Dongbing,
VásquezCéspedes Suhelen,
Glorius Frank
Publication year - 2015
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201410342
Subject(s) - rhodium , substituent , catalysis , intermolecular force , nucleophile , chemistry , medicinal chemistry , organic chemistry , molecule
A Rh III ‐catalyzed C–H activation/cyclative capture approach, involving a nucleophilic addition of C(sp 3 )–Rh species to polarized double bonds is reported. This constitutes the first intermolecular catalytic method to directly access 1‐aminoindolines with a broad substituent scope under mild conditions.