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Highly Enantioselective Adsorption of Small Prochiral Molecules on a Chiral Intermetallic Compound
Author(s) -
Prinz Jan,
Gröning Oliver,
Brune Harald,
Widmer Roland
Publication year - 2015
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201410107
Subject(s) - intermetallic , enantioselective synthesis , adsorption , enantiomer , catalysis , molecule , materials science , combinatorial chemistry , organic chemistry , chemical engineering , chemistry , alloy , engineering
Abstract Intrinsically chiral surfaces of intermetallic compounds are shown to be novel materials for enantioselective processes. Their advantage is the significantly higher thermal and chemical stability, and therefore their extended application range for catalyzed chiral reactions compared to surfaces templated with chiral molecular modifiers or auxiliaries. On the Pd 1 ‐terminated PdGa(111) surface, room‐temperature adsorption of a small prochiral molecule (9‐ethynylphenanthrene) leads to exceptionally high enantiomeric excess ratios of up to 98 %. Our findings highlight the great potential of intrinsically chiral intermetallic compounds for the development of novel, enantioselective catalysts that can be operated at high temperatures and potentially also in harsh chemical environments.