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Back Cover: Fluxionally Chiral DMAP Catalysts: Kinetic Resolution of Axially Chiral Biaryl Compounds (Angew. Chem. Int. Ed. 44/2014)
Author(s) -
Ma Gaoyuan,
Deng Jun,
Sibi Mukund P.
Publication year - 2014
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201408268
Subject(s) - kinetic resolution , catalysis , chirality (physics) , enantiomer , axial symmetry , chemistry , kinetic energy , cover (algebra) , combinatorial chemistry , stereochemistry , enantioselective synthesis , organic chemistry , physics , chiral symmetry , particle physics , mechanical engineering , quantum mechanics , quark , nambu–jona lasinio model , engineering
Place a pair of enantiomers in a box, wave a magic wand (a chiral catalyst), and two enantioenriched compounds pop out because of their differential interaction with the catalyst. In their Communication on page 11818 ff., M. P. Sibi et al. demonstrate that a novel 4‐dimethylaminopyridine catalyst with fluxional chirality is efficient in promoting acylative kinetic resolution of axially chiral biaryl compounds with selectivities of up to 51:1.