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Back Cover: Simultaneous Assessment of Kinetic, Site‐Specific, and Structural Aspects of Enzymatic Protein Phosphorylation (Angew. Chem. Int. Ed. 36/2014)
Author(s) -
van de Waterbeemd Michiel,
Lössl Philip,
Gautier Violette,
Marino Fabio,
Yamashita Masami,
Conti Elena,
Scholten Arjen,
Heck Albert J. R.
Publication year - 2014
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201406162
Subject(s) - cover (algebra) , phosphorylation , enzyme , int , kinetics , chemistry , mass spectrometry , biochemistry , computational biology , protein phosphorylation , enzyme kinetics , biophysics , combinatorial chemistry , computer science , active site , biology , engineering , chromatography , protein kinase a , physics , mechanical engineering , operating system , quantum mechanics
Multiple aspects of protein phosphorylation can be addressed simultaneously by an analytical method described by A. J. R. Heck and co‐workers in their Communication on page 9660 ff. Their approach integrates native and bottom‐up mass spectrometry and provides insight into the site specificity, kinetics, and structural effects of this biochemical process.