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Anion Complexation and The Hofmeister Effect
Author(s) -
Carnegie Ryan S.,
Gibb Corinne L. D.,
Gibb Bruce C.
Publication year - 2014
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201405796
Subject(s) - hofmeister series , chemistry , cavitand , counterion , carboxylate , salt (chemistry) , ion , inorganic chemistry , binding site , organic anion , stereochemistry , computational chemistry , crystallography , supramolecular chemistry , organic chemistry , crystal structure , biochemistry
The 1 H NMR spectroscopic analysis of the binding of the ClO 4 − anion to the hydrophobic, concave binding site of a deep‐cavity cavitand is presented. The strength of association between the host and the ClO 4 − anion is controlled by both the nature and concentration of co‐salts in a manner that follows the Hofmeister series. A model that partitions this trend into the competitive binding of the co‐salt anion to the hydrophobic pocket of the host and counterion binding to its external carboxylate groups successfully accounts for the observed changes in ClO 4 − affinity.