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Highly Enantioselective [3+2] Coupling of Indoles with Quinone Monoimines Promoted by a Chiral Phosphoric Acid
Author(s) -
Liao Lihua,
Shu Chang,
Zhang Minmin,
Liao Yijun,
Hu Xiaoyan,
Zhang Yonghong,
Wu Zhijun,
Yuan Weicheng,
Zhang Xiaomei
Publication year - 2014
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201405689
Subject(s) - enantioselective synthesis , phosphoric acid , quinone , chemistry , coupling (piping) , organic chemistry , combinatorial chemistry , catalysis , materials science , metallurgy
Highly enantioselective [3+2] coupling of 3‐substituted indoles with quinone monoimines promoted by a chiral phosphoric acid has been reported. A large variety of benzofuroindolines were prepared in moderate to good yields (up to 98 %) with generally excellent enantioselectivities (up to 99 % ee ).

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