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Pure In‐Phase Heteronuclear Correlation NMR Experiments
Author(s) -
Castañar Laura,
Saurí Josep,
Williamson Robert Thomas,
Virgili Albert,
Parella Teodor
Publication year - 2014
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201404136
Subject(s) - heteronuclear molecule , multiplet , coupling constant , phase (matter) , signal (programming language) , filter (signal processing) , physics , two dimensional nuclear magnetic resonance spectroscopy , nuclear magnetic resonance , chemistry , molecular physics , nuclear magnetic resonance spectroscopy , quantum mechanics , computer science , spectral line , computer vision , programming language
A general NMR approach to provide pure in‐phase (PIP) multiplets in heteronuclear correlation experiments is described. The implementation of a zero‐quantum filter efficiently suppresses any unwanted anti‐phase contributions that usually distort the multiplet pattern of cross‐peaks and can hamper their analysis. The clean pattern obtained in PIP‐HSQMBC experiments is suitable for a direct extraction of coupling constants in resolved signals, for a peak‐fitting process from a reference signal, and for the application of the IPAP technique in non‐resolved multiplets.