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Sugar‐based Molecular Computing by Material Implication
Author(s) -
Elstner Martin,
Axthelm Jörg,
Schiller Alexander
Publication year - 2014
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201403769
Subject(s) - adder , completeness (order theory) , electronic circuit , logic gate , computer science , construct (python library) , and gate , function (biology) , sugar , boronic acid , arithmetic , electronic engineering , algorithm , biological system , chemistry , mathematics , cmos , electrical engineering , combinatorial chemistry , engineering , biology , biochemistry , mathematical analysis , evolutionary biology , programming language
A method to integrate an (in principle) unlimited number of molecular logic gates to construct complex circuits is presented. Logic circuits, such as half‐ or full‐adders, can be reinterpreted by using the functional completeness of the implication function (IMP) and the trivial FALSE operation. The molecular gate IMP is represented by a fluorescent boronic acid sugar probe. An external wiring algorithm translates the fluorescent output from one gate into a chemical input for the next gate on microtiter plates. This process is demonstrated on a four‐bit full adder.