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Transient Substrate‐Induced Catalyst Formation in a Dynamic Molecular Network
Author(s) -
FanloVirgós Hugo,
Alba AndreaNekane R.,
Hamieh Saleh,
ColombDelsuc Mathieu,
Otto Sijbren
Publication year - 2014
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201403480
Subject(s) - catalysis , substrate (aquarium) , chemistry , synthetic biology , chemical engineering , materials science , nanotechnology , biophysics , combinatorial chemistry , biology , biochemistry , computational biology , engineering , ecology
In biology enzyme concentrations are continuously regulated, yet for synthetic catalytic systems such regulatory mechanisms are underdeveloped. We now report how a substrate of a chemical reaction induces the formation of its own catalyst from a dynamic molecular network. After complete conversion of the substrate, the network disassembles the catalyst. These results open up new opportunities for controlling catalysis in synthetic chemical systems.