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Simple but Precise Engineering of Functional Nanocapsules through Nanoprecipitation
Author(s) -
Yan Xibo,
Delgado Marco,
Fu Amy,
Alcouffe Pierre,
Gouin Sébastien G.,
Fleury Etienne,
Katz Joseph L.,
Ganachaud François,
Bernard Julien
Publication year - 2014
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201402825
Subject(s) - nanocapsules , hexadecane , polymer , nanoparticle , nanotechnology , acetone , molecule , chemistry , chemical engineering , materials science , organic chemistry , engineering
A general, rapid, and undemanding method to generate at will functional oil‐filled nanocapsules through nanoprecipitation is reported. On the basis of polymer and hexadecane/water/acetone phase diagrams, the composition can be set so that polymer chains preferentially stick at the interface of the oil droplets to create nanocapsules. The nanocapsules can be decorated with biorelevant molecules (biotin, fluorescent tags, metal nanoparticles) within the shell and loaded with hydrophobic molecules in a simple one‐pot procedure.