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Cover Picture: Silver(I)‐Catalyzed Hydroazidation of Ethynyl Carbinols: Synthesis of 2‐Azidoallyl Alcohols (Angew. Chem. Int. Ed. 21/2014)
Author(s) -
Liu Zhenhua,
Liu Jianquan,
Zhang Lin,
Liao Peiqiu,
Song Jinna,
Bi Xihe
Publication year - 2014
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201401134
Subject(s) - regioselectivity , catalysis , chemistry , cover (algebra) , organic chemistry , int , combinatorial chemistry , medicinal chemistry , computer science , mechanical engineering , engineering , operating system
The hydroazidation of unactivated alkynes is described by X. Bi and co‐workers in their Communication on page 5305 ff. Silver catalysis enabled the chemo‐ and regioselective transformation of ethynyl carbinols into vinyl azides. A wide variety of 2‐azidoallyl alcohols were obtained in good to excellent yields. The synthetic utility of 2‐azidoallyl alcohols was demonstrated by further transformations into NH aziridines.