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Inside Cover: Confining Phosphanes Derived from Cyclodextrins for Efficient Regio‐ and Enantioselective Hydroformylation (Angew. Chem. Int. Ed. 15/2014)
Author(s) -
Jouffroy Matthieu,
GramageDoria Rafael,
Armspach Dominique,
Sémeril David,
Oberhauser Werner,
Matt Dominique,
Toupet Loic
Publication year - 2014
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201401124
Subject(s) - hydroformylation , enantioselective synthesis , rhodium , cyclodextrin , chemistry , catalysis , organic chemistry
Metal confinement can make the difference, as shown by D. Matt, D. Armspach et al. in their Communication on page 3937 ff. The use of cyclodextrin derivatives with an introverted P III donor atom in the rhodium‐catalyzed hydroformylation of styrene leads to high iso‐ and enantioselectivity. This result is due to the selective formation of monophosphane complexes in which the cyclodextrin cavity tightly wraps around the metal center, like Russian nesting dolls (artwork: Katia Gradt).