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Citric Acid and the RNA World
Author(s) -
Müller Ulrich F.,
Tor Yitzhak
Publication year - 2014
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201400847
Subject(s) - citric acid , rna , chemistry , magnesium , chelation , biochemistry , inorganic chemistry , gene , organic chemistry
RNA world : The chelation of magnesium ions by citric acid prevents the magnesium‐induced aggregation of lipid vesicles and RNA degradation while promoting nonenzymatic RNA oligomerization. These findings suggest a unique role for this simple organic acid in supporting key processes in RNA world organisms.