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Bio‐Inspired Photonic‐Crystal Microchip for Fluorescent Ultratrace Detection
Author(s) -
Hou Jue,
Zhang Huacheng,
Yang Qiang,
Li Mingzhu,
Song Yanlin,
Jiang Lei
Publication year - 2014
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201400686
Subject(s) - analyte , fluorescence , fluorophore , nanotechnology , photonic crystal , materials science , detection limit , chemistry , optoelectronics , chromatography , optics , physics
Abstract Ultratrace detection attracts great interest because it is still a challenge to the early diagnosis and drug testing. Enriching the targets from highly diluted solutions to the sensitive area is a promising method. Inspired by the fog‐collecting structure on Stenocara beetle’s back, a photonic‐crystal (PC) microchip with hydrophilic–hydrophobic micropattern was fabricated by inkjet printing. This device was used to realize high‐sensitive ultratrace detection of fluorescence analytes and fluorophore‐based assays. Coupled with the fluorescence enhancement effect of a PC, detection down to 10 −16 mol L −1 was achieved. This design can be combined with biophotonic devices for the detection of drugs, diseases, and pollutions of the ecosystem.