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Inside Cover: Total Synthesis of (±)‐Aspidophylline A (Angew. Chem. Int. Ed. 7/2014)
Author(s) -
Ren Weiwu,
Wang Qian,
Zhu Jieping
Publication year - 2014
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201400427
Subject(s) - total synthesis , cover (algebra) , intramolecular force , int , stereochemistry , michael reaction , key (lock) , monoterpene , chemistry , computer science , organic chemistry , programming language , engineering , mechanical engineering , computer security , catalysis
The total synthesis of the monoterpene alkaloid aspidophylline A is described by J. Zhu and et. al. in their Communication on page 1818 ff. The concise synthetic strategy features rapid access to the pentacyclic skeleton of aspidophylline A by using intramolecular Michael additions as key steps. The strategy could potentially provide a feasible route to other congeners of the akuammiline family of alkaloids.